Using a Diablo 4 world boss loot table is the quickest and easiest way to work out what Unique items each of the newly introduced big bads drop. There are four new bosses being added alongside the Season of Blood and each of them has a loot table for possible Unique items they can drop. Yes, that means you can finally target-farm for that build-defining unique you’re missing instead of just living in hope.
What’s more, these bosses are also being added to the eternal realm, meaning you can use any high-level characters you already have to try them out as soon as the season launches—provided you gather the materials necessary to summon them, that is. Each boss is tied to a particular activity, so you’ll have to complete a fair bit to gather the necessary components.
All that said, here are all of the Diablo 4 boss loot tables, plus an explanation of what you need to do to summon each.
Diablo 4 Varshan loot table
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You can re-fight Varshan from the Season of the Malignant in Nightmare and Torment world tier. If you complete Whispers and randomly acquire his Malignant body parts, you can summon him below the Tree of Whispers. Here’s what he can drop:
Diablo 4 Grigoire loot table
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You can fight Grigoire, the Galvanic Saint in Nightmare and Torment world tier if you earn Infernal Steel through Helltides to summon him. Here’s what he drops:
Diablo 4 Lord Zir loot table
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While there is a story version of this boss, you can fight Lord Zir in the Torment world tier if you kill world bosses and complete legion events to acquire the materials to summon him. Here’s what he drops:
Diablo 4 Beast in Ice loot table
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You can fight the Beast in Ice in the Torment world tier if you complete Nightmare Dungeons above tier 30 and gather the components to create its special Nightmare Dungeon key. Here’s what it drops:
Diablo 4 Duriel loot table
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You can fight Duriel, King of Maggots in the Torment world tier if you acquire the components to summon him by defeating other bosses like Varshan and Grigoire. Here’s what the boss can drop, including Uber Uniques: